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  1. Clinical Pharmacology clinical pharmacology Mechanism Of Action Although the exact mechanism of prozac is unknown, it is presumed to be linked to its inhibition fluoxetine hcl of CNS neuronal uptake of serotonin. Geller DA, Hoog SL, Heiligenstein JH. Double-blind comparison of fluoxetine and amitriptyline in the treatment of major depressive illness.

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